dominio basal de celula con lamina basal. desmosomas. Hemidesmosomas. son especializaciones de membranas plasmaticas. une. uniones. Adhesiones laterales entre las células epiteliales a través de proteínas que vinculan el citoesqueleto de las células contiguas. Integrinas α6β4. cel. • Ampliamente distribuidas en animales. • Formada por un estrecho canal. DESMOSOMAS EN BANDA Uniones focales que unen células.

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Muchos de ellos ceden al tratamiento pero otros pueden generar complicaciones graves lo que depende de la respuesta inmune del paciente.

The approximation to Pemphigus-like lesions that occur in the oral cavity are based on clinical appearance, systemic manifestations, diagnostic criteria, and pathophysiology. This is described as a blister hemidesnosomas by the separation between the desmosomal junctions due to the presence of autoantibodies against adhesion proteins, the desmogleins.

Differential diagnosis is pemphigoid and etiology of hereditary or external causes such as ultraviolet radiation, diet, pesticides, drugs, among others. The characteristic presentation feature is a blister with serous fluid which manifests as mucosal sites and skin. It is classified into three main varieties, the vulgar, the foliaceus and paraneoplastic.

Its diagnosis is given by clinical appearance and laboratory tests biopsy, etc. Treatment includes the use of topical and systemic corticosteroids, starting with high doses and subsequently with low maintenance stages. Many improve with treatment, but some may lead to serious complications, which depending on the patient’s immune response.

Pemphigus, Descamative gingivitis, Desmoglein, Autoantibodies, Corticosteroids. Los estados bacterianos como la influencia del S. En forma temprana puede confundirse con una dermatitis seborreica. En cavidad oral son poco comunes. La Dsg predominante es la 1. El paraneoplasico difiere del vulgar desmosomxs el compromiso de las palmas y plantas. Como terapia desmosomws los pacientes a menudo requieren ingestas hemidesmosomss calcio, bifosfonatos y vitamina D.


Cuando el paciente es recurrente se formula fluconazol 2 veces por semana.

Desmosoma – Wikipedia, a enciclopedia libre

En el paraneoplasico los esteroides son considerados hemidesmosomxs paliativo por su pobre respuesta. Se han recomendado medicamentos adjuntos como metrothexate, ciclofosfamida, 50 azatioprina, micofenolato y mofetilo con ciclosporinas. Su frecuencia baja, con reportes entre 1 a 5 personas por millon. Interventions for pemphigus vulgaris and pemphigus foliaceus. Cochrane Database Syst Rev.

Oral pemphigus vulgaris in a pediatric patient.


Internalization of constitutive desmogleins with the subsequent induction of desmoglein 2 in pemphigus lesions. Wananukul S, Pongprasit P. Analysis of antigens targeted by circulating IgG and IgA antibodies in patients with mucous membrane pemphigoid predominantly affecting the oral cavity.

A determination of the range of oral conditions submitted for microscopic and direct immunofluorescence analysis. Allen CM, Camisa C. Twenty-eight-year-old woman with recent onset of painful oral erosions. IgA pemphigus-occurrence of anti-desmocollin 1 and anti-desmoglein 1 antibody reactivity in an individual patient.

J Dtsch Dermatol Ges. J Eur Acad Dermatol Venereol. Epidemiology of pemphigus in Macedonia: The management of mucous membrane pemphigoid and pemphigus. Pemphigus and associated environmental factors: Gingival lesions diagnosed as pemphigus vulgaris in an adolescent. Desmosomaas features of gingival pemphigus vulgaris. Comparative study of pemphigus vulgaris and pemphigus foliaceus in Singapore.

Esthetic management of multiple recession defects in a patient with cicatricial pemphigoid. Early detection and successful management of oral pemphigus vulgaris: Periodontal status in patients with hemiddsmosomas mucous membrane pemphigoid.


Immunopathological diagnosis of cicatricial pemphigoid with desquamative gingivitis. Guidelines for the management of pemphigus vulgaris. A comparison of the periodontal status in patients with mucous membrane pemphigoid: Drug-related pemphigus and angiotensin converting enzyme inhibitors. The molecular logic of pemphigus and impetigo: Disease progression from mucosal to mucocutaneous involvement in a patient with desquamative gingivitis associated with pemphigus vulgaris.

Update on the cloning of hemideamosomas anti-desmoglein antibodies from human pemphigus patients: Chowdhury MM, Natarajan S. Neonatal pemphigus vulgaris associated with mild oral pemphigus vulgaris in the mother during pregnancy. Mc Graw Hill; Clinical and histopathological features of pemphigus foliaceus with and without eosinophilic infiltrates: Paraneoplastic pemphigus characterized by polymorphic oral mucosal manifestations–report of two cases.

Diagnostic pathways and clinical significance of desquamative gingivitis. Immunofluorescence of the outer root sheath: Pemphigus vulgaris and internal malignancy. Iraji F, Banan L. Damoulis PD, Gagari E. Combined hemidesmosomax of periodontal disease and benign mucous membrane pemphigoid.

Case report with 8 years maintenance. Cyclosporine A-induced gingival hyperplasia pemphigus vulgaris: Services on Demand Article.

Spanish pdf Article in xml format Article references How to cite this article Automatic translation Send this article by e-mail. Abstract The approximation to Pemphigus-like lesions that occur in the oral cavity are based on clinical appearance, systemic manifestations, diagnostic criteria, and pathophysiology.

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