The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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Marcel Dekker Inc; All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. This article has been cited by other articles in PMC.

Optimization of chlorphenesin emulgel formulation

Preparation of an emulgel for treatment of aphthous ulcer on the basis of carbomers. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types enulgel gelling agents: The Theory and Practice of Industrial Pharmacy.

A study of shear and compression deformations on formulztion gels of tretinoin. Az J Pharm Sci. The Pharmaceutical Press; Formulation and stability of chloramphenicol gel and emulgel.

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The drug release from all the emulgels was found to follow diffusion-controlled mechanism.

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Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Commercially available CHL topical powder was used for comparison. Published online Sep 1.

Support Center Support Center. Blackwell Scientific Publications; Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. Author information Article notes Copyright and License information Disclaimer.

Egypt J Pharm Sci. Encyclopedia of Pharmaceutical Technology. Transdermal controlled release systems. Bioavailability of salbutamol sulphate from different suppository formulations.

Please review our privacy policy. The prepared emulgels were evaluated for their physical appearance, rheological behavior, drug release, antifungal activity, and stability.

Lea and Febiger; Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy.

As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity. Analysis of data on the medicament release from ointments. Swarbrick J, Boylan JC, editors.


Formulation and evaluation of topical preparations containing phenol and local vesicants. Stability studies showed that the physical appearance, rheological properties, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months.

The Complete Drug Reference.

Optimization of chlorphenesin emulgel formulation

They also exhibited higher drug release and antifungal activity than the CHL powder. Received Dec 31; Accepted May The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design.

It was found that formulatino emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent. National Center for Biotechnology InformationU. Medical Applications of Controlled Release.