EPIDERMOLISIS BULLOSA SIMPLE PDF
Epidermolysis bullosa simplex is one of a group of genetic conditions called epidermolysis bullosa that cause the skin to be very fragile and to blister easily. Epidermolysis bullosa (EB) is a group of genetic conditions that result in easy blistering of the skin and mucous membranes. Blisters occur with minor trauma or . Prevención de Ampollas. Como cargar al bebé: Evite levantar el bebé o niño por debajo de los brazos. En su lugar, ponga una mano debajo del trasero y la otra.
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El vendaje no-adhesivo puede ser asegurado con gasa enrollada y finalmente con un retenedor tubular de vendaje como Spandage o Surgilast.
Epidermólisis Bullosa Simple by Maria Fernanda Marenco Salazar on Prezi
The human skin consists of two layers: Ten genes are known to harbor mutations in the major types of EB, and the level of expression of these genes within the cutaneous basement membrane zone and in extracutaneous tissues, as well as the types and combinations of the mutations, explain, in general terms, the phenotypic variability Following the patient’s conditioning therapy, the surgical procedures were carried out in 5 weekly appointments Figure 3A.
It also presents with blisters at the site of friction, especially on the hands and feet, and has variants that can occur in children and adults. Epidermolysis bullosa simplex is a form of epidermolysis bullosa that causes blisters at the site of rubbing. August 31, Accepted: A person with an autosomal dominant disorder — in this case, the father — has a 50 percent chance of having an affected child with one mutated gene dominant gene and a 50 percent chance of having an unaffected child with two normal genes recessive genes.
It has also been designed to evaluate the response to new therapies for the treatment of EB. The aim of this article is to describe two dental clinical treatments of recessive dystrophic EB cases and their specific clinical manifestations.
D ICD – It typically affects the hands and feet, and is typically inherited in an autosomal dominant manner, affecting the keratin genes KRT5 and KRT She also presented ankyloglossia and microstomia, probably due to secondary scars from repeated episodes of blistering and subsequent healing. This disease is characterised by blister formation within the lamina lucida of the basement membrane zone : A second transplant has also been performed on the child’s older brother, and a third transplant is scheduled for a California baby.
Daily wound care, pain management, and protective bandaging are the only options available for people with EB.
The major dental complication of EB in general is the increased risk of caries 3. Most types of epidermolysis bullosa are inherited. Epidermolysis bullosa can be diagnosed either by a skin punch biopsy at the edge of a wound with immunofluorescent mapping, or via blood sample and genetic testing.
Types of Epidermolysis Bullosa
Less than one person per million people is estimated to have this form of epidemolysis bullosa. There are four major types of EB based on the site of blister formations within the skin layers: Periodontal plastic surgery in a dystrophic epidermolysis bullosa patient: The patient’s mental status was appropriate for her age.
The severity of EB is generally dependent upon many factors including type, subtype, and inheritance pattern.
Onset of the disease is usually at birth. In this type, blistering occurs in a skin layer called the lamina lucida within the basement membrane zone, which is situated at the junction between the epidermis upper layer of the skin and the dermis lower layer.
Epidermolysis bullosa EB is a group of genetic conditions that result in easy blistering of the skin and mucous membranes. Aplasia cutis congenita Amniotic band syndrome Branchial cyst Cavernous venous malformation Accessory nail of the fifth toe Bronchogenic cyst Congenital cartilaginous rest of the neck Congenital hypertrophy of the lateral fold of bullsoa hallux Congenital lip pit Congenital malformations of the bulloa Congenital preauricular fistula Congenital smooth muscle hamartoma Cystic lymphatic malformation Median raphe cyst Melanotic neuroectodermal tumor of infancy Mongolian spot Nasolacrimal duct cyst Omphalomesenteric duct cyst Poland anomaly Rapidly involuting congenital hemangioma Rosenthal—Kloepfer syndrome Skin dimple Superficial lymphatic malformation Thyroglossal duct cyst Verrucous vascular malformation Birthmark.
Congenital malformations and deformations of skin appendagesTemplate: The treatment for patients with EB is multidisciplinary and, unfortunately, no epidermollsis therapeutic regimen can cure the disease 7,8. What is Epidermolysis Bullosa EB?
The restorative treatment using glass ionomer cement was accomplished within 5 weeks.
Oral lesions in recessive dystrophic epidermolysis bullosa. It usually occurs at birth, but sometimes the symptoms are mild and detected only when the child is older.
To have an autosomal recessive disorder, you inherit two mutated genes, one from each parent. This content does not have an Arabic version. As a result, severe forms of the disease may be fatal. Thus, conditioning sessions were adopted in order to obtain the patient’s trust.
Two case reports with year follow-up. EB has been categorized as encompassing 5 major types Simplex, Junctional, Dystrophic, Kindler Syndrome, Aquisita and 31 subtypes, therefore it is commonly referred to as a group of disorders.
Furthermore, as a complication of the chronic skin damage, people suffering from EB have an increased risk of malignancies cancers of the skin.